Scientist Bioreactor Process Design

Il y a 2 mois


Toulouse, France Evotec Temps plein

Scientist Bioreactor Process Design (all genders)

Permanent contract

Just-Evotec Biologics is looking for a Scientist of Bioreactor Process Design to join a fast-paced, collaborative, and multidisciplinary team working on upstream process development (perfusion and intensified fed-batch) projects. In this role, you will participate in further developing and refining Just’s next-generation continuous bioprocessing platform, which we are currently running in our Seattle and Redmond manufacturing facilities at 500L and 1000L scale. Just-Evotec employees are driven by our mission: to expand access to therapeutics by substantially driving down the cost of goods through process technology development. This role is well-positioned to have a substantial impact on patients and the biotechnology industry.

This position will be part of a team to perform upstream process development for early and late-stage processes and will include process development, optimisation, characterization, and technology transfer for intensified, continuous processes. The successful candidate will be detail-oriented, self-motivated, efficient, curious, and work well in a team environment. Strong written and verbal communication skills, including the ability to communicate effectively over teleconferences and web-based meetings, are necessary.


Responsibilities:

Developing and/or assisting upstream processes for biotherapeutics manufacturing

Designing, executing, and analysing statistically designed experiments (DOE) either independently or with support from manager

Ensure accurate and complete documentation of lab activities and write appropriate technical reports for successful regulatory submission.

Ensure the upstream development (USP) labs and equipment is maintained under optimal working conditions and assume responsibility for specific instruments.

Contribute to investigations (e.g., deviations) as required to help identify the root cause and propose and implement appropriate corrective actions. 

Carry out Development/Characterisation/optimisation experiments, accurately document results, and produce experimental reports.

Support tech transfer with manufacturing organizations (internal and external)

Responsible for own professional attitude and for sharing knowledge for the benefit of others or on demand.

Author, amend and review operating documents, such as SOPs, guidelines, and data records. Willing to take on additional activities.

Documenting best practices and technical results in ELNs, SOPs, summary reports, etc.

Working with vendors and manufacturers

Assisting with bench-scale bioreactor operations including run preparation, bioreactor assembly, autoclave, inoculation, daily sampling and analytics, troubleshooting, cleaning, and maintenance

Potential for weekend work (5-day work week/ 2 consecutive days off)

FR : Dans le cadre de sa politique Diversité, Evotec étudie, à compétences égales, toutes les candidatures dont celles des personnes en situation de handicap.

ENG : In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities.



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