PhD Thesis Student
il y a 1 mois
Context & Job description
Subject: Probing protein dynamics by single-crystal room temperature, or high-pressure cryogenic, crystallography and in crystallo optical spectroscopy
You will join the Structural Biology Group to pursue a project aimed to propose a new paradigm in macromolecular crystallography (MX) by focusing on room temperature data collection and embracing complementary biophysical approaches. Single-crystal room temperature MX has the potential to probe proteins dynamics, benefitting from the use of complementary techniques (e.g., optical spectroscopy, high-pressure) directly used on crystalline samples. This integrated project, combining MX, in crystallo optical spectroscopy (icOS) and high-pressure MX (HPMX), will study several fluorescent proteins in order to provide a comprehensive picture of their dynamics to help tune their properties.
Expected profile
Degree allowing enrolment for a PhD (such as MSc, Master 2 de Recherche, Laurea or equivalent) in biology, biophysics or a closely related science A background in structural biology or biophysical methods is desirable Ability to interact within a multi-disciplinary team Wide interest between instrumentation, methodology and applied biological research Proficiency in English (working language at the ESRF)
Working conditions
Your shall be enrolled in Université Grenoble Alpes / Chemistry & Life Doctoral School as a condition of your recruitement.
Contract of two years renewable for one year.
Do you recognize yourself in this description? Apply now for your next professional adventureWhat we offer:
Join an innovative international research institute, with a workforce from 38 different countries Collaborate with global experts to advance science and address societal challenges Come and live in a vibrant city , in the heart of the Alps, and Europe's Green Capital 2022 Enjoy a workplace designed to support your quality of life Benefit from our competitive compensation and allowances package , including financial support for your relocation to Grenoble-
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