Senior Scientist, Cellular

Il y a 5 jours

Dreux, Centre-Val de Loire, France Ipsen Pharma SAS Temps plein 90 000 € - 130 000 € Contrat

Title:
Senior Scientist, Cellular & Translational Sciences, OneLab

Company:
Ipsen Innovation (SAS)

About Ipsen:

Ipsen is a mid-sized global biopharmaceutical company with a focus on transformative medicines in three therapeutic areas: Oncology, Rare Disease and Neuroscience. Supported by nearly 100 years of development experience, with global hubs in the U.S., France and the U.K, we tackle areas of high unmet medical need through research and innovation.

Our passionate teams in more than 40 countries are focused on what matters and endeavor every day to bring medicines to patients in 88 countries. We build a workplace that champions human-centric leadership and fosters a culture of collaboration, excellence and impact. At Ipsen, every individual is empowered to be their true selves, grow and thrive alongside the company’s success. Join us on our journey towards sustainable growth, creating real impact on patients and society

For more information, visit us at https://www.ipsen.com/ and follow our latest news on LinkedIn and Instagram .

Job Description:

WHAT - Summary & Purpose of the Position

The Senior Scientist, Cellular & Translational Sciences, OneLab is a senior laboratory-based scientific leader responsible for advancing Ipsen’s R&D portfolio across therapeutic areas, including Oncology, Rare Diseases and Neuroscience, through the development and application of cutting-edge cellular characterization, functional and translational approaches.

The role provides scientific and operational leadership for preclinical and translational laboratory activities, with particular expertise in high-dimensional flow cytometry, cellular profiling and functional cellular assays. The position drives the generation of decision-enabling data supporting target validation, candidate selection, mechanism-of-action and pharmacodynamic studies, biomarker discovery and clinical translation.

As a recognized subject matter expert in flow cytometry and cellular profiling, the individual will lead the development of innovative experimental strategies applicable across therapeutic areas, oversee laboratory capabilities, manage scientists and/or postdoctoral researchers, and contribute to portfolio decisions through deep scientific expertise and cross-functional collaboration.

WHAT - Main Responsibilities & Technical Competencies

Scientific Leadership

Provide scientific leadership for cellular and translational laboratory activities across multiple research and development programs and therapeutic areas, including Oncology, Rare Diseases and Neuroscience.

Generate mechanistic and translational scientific insights that inform drug discovery, candidate progression and development strategies.

Partner with project and cross-functional teams to translate biological questions into robust experimental strategies and decision-enabling data.

Identify, evaluate and implement emerging technologies and innovative approaches relevant to cellular biology, translational science and drug development.

Contribute scientific expertise to portfolio and project decisions across different modalities, mechanisms of action and disease areas.

Advanced Flow Cytometry & Cellular Profiling Expertise

Act as Ipsen’s laboratory subject matter expert for advanced flow cytometry and cellular profiling applications across therapeutic areas.

Design, implement and continuously improve complex multi-parameter and spectral flow cytometry panels.

Develop cellular profiling strategies to characterize disease-relevant cell populations, cellular phenotypes, target expression, pathway modulation and pharmacological responses.

Develop and qualify robust assays enabling characterization of cell identity, activation state, functional responses, target engagement, pharmacodynamic effects and mechanisms of action.

Establish best practices for assay design, panel optimization, data quality, reproducibility and quantitative data analysis.

Drive innovation in single-cell, high-content and multimodal cellular profiling technologies.

Provide scientific guidance on the interpretation and biological relevance of complex cellular datasets.

Establish and maintain efficient technology-transfer processes for internally developed assays to external partners and CROs, ensuring reproducibility, quality and compliance.

Laboratory Leadership

Lead laboratory activities for advanced flow cytometry supporting research objectives.

Ensure scientific excellence, data integrity and compliance with laboratory standards.

Oversee study design, execution, data analysis and reporting of pharmacological reports.

Develop laboratory capabilities and contribute to strategic investment and technology roadmaps.

Manage external laboratories and CRO collaborations when req