Research Engineer
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Organisation/Company INSERM Department U1312 Research Field Biological sciences » Biology Researcher Profile First Stage Researcher (R1) Positions Research Support Positions Application Deadline 23 Oct 2026 - 23:59 (Europe/Paris) Country France Type of Contract Temporary Job Status Full-time Hours Per Week 38.5 Offer Starting Date 1 Dec 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No
Offer Description
Host Research Unit
The BoRdeaux Institute of onCology (BRIC) is a research unit located at the University of Bordeaux. Jointly accredited by Inserm and the University of Bordeaux, BRIC brings together the existing cancer research expertise in Bordeaux, with approximately 260 people working in 11 research teams and four shared services. The successful candidate will join Team 7.
We are seeking a candidate with strong knowledge of cell biology and bioinformatics for a fixed term (CDD) Research Engineer (Ingénieur d’études) position within the team.
Main Mission
Mammary organoid culture and bioinformatic analysis of spatial transcriptomics data.
Main Activities
The successful candidate will carry out the following activities:
- 3D culture of mammary organoids in Clevers medium
- Cell aggregation in AggreWells
- Seeding of organoids in hydrogel domes in 96-well plates
- Organoid culture using Incucyte/CellCyte
- Bioinformatic analysis of Incucyte/CellCyte data and spatial transcriptomics data
Candidates must have knowledge of:
- Molecular and cellular biology
- Breast cancer biology
- Bioinformatics
Requirements
Research Field Biological sciences » Biology Education Level Master Degree or equivalent
Skills/Qualifications
Candidates must have skills in:
- 3D organoid culture in Clevers medium
- Aggregation of primary cells in AggreWells
- Lentiviral infection of primary cells
- Seeding of organoids in 96-well plates
- R and Python programming from YAML in VS Code
- Statistical analyses using mixed models
Personal Skills
The candidate should demonstrate:
- A genuine service-oriented attitude, good listening skills and discretion
- Curiosity and the ability to seek out relevant information
- Ability to integrate into a team and work collaboratively
- Scientific integrity and rigour
Specific Requirements
Experience in the following is desired:
- 3D culture of mammary organoids
- Culture using Incucyte/CellCyte or a similar system
- Flow cytometry
- Molecular cloning, qPCR and Western blotting
- Spatial transcriptomics analysis, preferably Visium or Xenium
- R/Bioconductor and Python for bulk, single-cell and spatial transcriptomics, including Seurat, scanpy, anndata, squidpy and proseg
- Image analysis using ImageJ, QuPath and Python
Annual leave and RTT are provided according to Inserm rules.
Remote Working
This position is not eligible for remote working.
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