Immuno-oncology in Vitro Study Manager

il y a 4 jours

Bordeaux, France EXPLICYTE Temps plein

**Immuno-Oncology **_**in vitro**_ **Study Manager**

**Job offer #**:SM0624**

**Type**: Full time position, permanent contract

**Location**:Bordeaux, France

**You are passionate about the interplay between immune and tumor cells? You have experience with 2D and 3D models? You master flow cytometry and other multiparametric platforms for in vitro analysis? The perspective of testing innovative cancer immunotherapies creates some excitement? Keep reading and apply**

**About Explicyte**

**Explicyte is a preclinical and translational contract research organization specialized in immuno-oncology. **Our goal is to assist academics, biotechs and pharmas in the discovery of novel targets and novel cancer immunotherapies.

**With a team of 25, we’re a human-sized company**, which brings under the same roof cell biologists, immunologists, _in vivo _scientists, medical oncologists and bioinformaticians. **Focused on sponsors’ projects**, our activity also involves in-house R&D and external collaborations, which led to the publication of **25+ papers in high impact-factor journals.**

**Based in Bordeaux, our lab is located at the Bergonié Comprehensive Cancer Center**, where we work in close contact with medical oncology teams. We believe **Explicyte is a place to learn, grow, and have impact in the fight against cancer.**

**Your position**

To strengthen and expand our in _vitro_ team and activities, we are looking for an **experienced **_**in vitro **_**Immuno-Oncology Scientist**, ready to take up with us the **setup of new **_**in vitro **_**platforms and assays**, relevant for the testing and development of novel immunotherapeutic strategies.

In your role, you will be responsible for the **technical and organizational management of sponsors’ and in-house R&D **_**in vitro **_**studies**, from their implementation and performance to data analysis. You will timeously provide deliverables with respect to the project’s requirements and timelines.

You will interact closely with the _in vitro _team members, and will report to study directors and to the CSO.

**Your skills & traits**
- **Ph.D - **or equivalent - in science and health-related field
- **Minimum 2 years of experience **in preclinical development in the health industry: Pharma, Biotech, CRO
- Broad understanding of **tumor immunology **and/or cancer therapies
- **Expertise** **in cell culture protocols **(eg. 2D, 3D, immune/tumor cell co-cultures, immune cell isolation and cultivation, differentiation and polarization protocols)
- Mastery of multiparametric analysis methodologies, mainly in **flow cytometry**
- **Project management** experience (from planning to closing projects)
- **Excellent diligence**
- **Strong interpersonal **& **organizational** skills
- **Ability** to **easily adapt** to changing priorities and challenges
- **Enthusiasm, curiosity, and integrity**

**Your missions & responsibilities**
- **Provide draft protocols** according to the proposed scientific and experimental strategies
- **Implement studies**:

- relying on undeniable organizational skills - according to their design and established schedules
- **Manage and perform**:

- diligently - _**in vitro and ex-vivo **_**experiments**
- Cell culture-based experiments for functional immuno-oncology assays: with human and rodent cell origins, with tumor and/or immune cells (PBMCs, T cells, macrophages, tumor-infiltrating leukocytes ), and requiring immune cell isolation and cultivation, differentiation, polarization, etc
- 3D approaches: spheroids, organoids, and patient-derived tumor samples and their use in preclinical research and therapeutic assessment
- _Ex vivo _processing of collected samples for immune or tumor cell isolation, or for further analyses (FACS, ELISA )
- **Capture, analyze and compile data**, including quality controls
- **Ensure accuracy and completeness of study documentation **and timely provide study deliverables
- **Write internal protocols and standard operating procedures**
- **Contribute to experimental development **by implementing new methods and training other collaborators and team’s members

Type d'emploi : Temps plein, CDI
Statut : Cadre

Rémunération : 30 000,00€ à 45 000,00€ par an

Avantages:

- Crèche d'entreprise
- Prise en charge du transport quotidien

Programmation:

- Du lundi au vendredi
- Travail en journée

Lieu du poste : En présentiel

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