Phd Position in Medicinal Bioinorganic Chemistry:

il y a 2 semaines


Marseille, France Institut des Sciences Moléculaires de Marseille UMR CNRS 7313 Aix-Marseille Université Temps plein

**PhD position in medicinal bioinorganic chemistry: development of redox-active copper complexes for cancer therapy**:

- Réf **ABG-122873**
- Sujet de Thèse- 15/04/2024- Contrat doctoral- Institut des Sciences Moléculaires de Marseille UMR CNRS 7313 Aix-Marseille Université- Lieu de travail- Marseille - Provence-Alpes-Côte d'Azur - France- Intitulé du sujet- PhD position in medicinal bioinorganic chemistry: development of redox-active copper complexes for cancer therapy- Champs scientifiques- Chimie
- Biologie
- Santé, médecine humaine, vétérinaire
- Mots clés- Copper complexes, cancer, peptides, cytotoxicity, cell death mechanism**Description du sujet**:

- ContextGlioblastoma is the most common and aggressive primary brain tumor in humans, with a median survival of around 15 months. Standard treatment (STUPP protocol) has not been modified since 2005 and, although tumors generally relapse, no significant improvement has been achieved clinically in recent years using alternative approaches, such as anti-angiogenic treatments and immunotherapies. This represents an unmet need.
- PhD Project**Prise de fonction**:

- 01/10/2024**Nature du financement**:

- Contrat doctoral**Précisions sur le financement**:
**Présentation établissement et labo d'accueil**:

- Institut des Sciences Moléculaires de Marseille UMR CNRS 7313 Aix-Marseille Université**Aix-Marseille Université (AMU) **est née en 2012, de la fusion des 3 universités de Marseille et d'Aix. Elle est aujourd'hui la plus importante en termes d'effectifs étudiants (+ 80 000 étudiants), mais aussi de corps professoral et de personnel (+ 8 000 personnes) et de budget, de toute la francophonie. AMU représente 12 écoles doctorales et près de 3 000 doctorants. Elle abrite 122 équipements de recherche liés aux plus grandes institutions de recherche françaises (CNRS, INSERM, IRD, INRA, CEA). Dans le dernier classement international de Shanghai, AMU est positionnée comme la 101ème meilleure université (5ème place parmi les universités françaises).

Le **Centre national de la recherche scientifique (CNRS)** est un organisme public de recherche interdisciplinaire placé sous la tutelle administrative du ministère français de l'Enseignement supérieur et de la Recherche. Le CNRS est le principal organisme de recherche fondamentale en Europe, largement impliqué dans des projets nationaux, européens et internationaux couvrant tous les domaines de la connaissance et reconnu pour son excellence avec 21 prix Nobel et 12 médailles Field. Le CNRS compte 32000 employés dans plus de 1200 services, avec un budget de 3,4 milliards d'euros et plus de 1100 unités de recherche réparties dans le monde entier.

**Intitulé du doctorat**:

- Doctorat de Chimie**Pays d'obtention du doctorat**:

- France**Ecole doctorale**:

- École Doctorale des sciences chimiquesA good level of oral and written English will be appreciated to integrate into this international team.- 31/05/2024



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