Project Manager
il y a 1 jour
OverviewWe are seeking a Project Manager to join our team who specializes in Beyond Rule of 5 (bRo5) molecules and can lead cross-functional CMC development programs for complex, non-traditional small molecules.This role is central to coordinating technical strategy, timelines, and execution across discovery, development, and manufacturing for challenging chemical entities with unique solubility, permeability, and bioavailability profiles.The successful candidate will act as the integration point between chemistry, formulation, process development, analytical, regulatory, and external partners, ensuring technically sound and executable development plans.Key ResponsibilitiesLead end-to-end CMC project management for bRo5 molecules, including macrocycles, peptides, and other complex chemotypes.Coordinate development strategies addressing solubility, permeability, stability, and exposure challenges typical of bRo5 compounds.Ensure alignment between discovery, preclinical, and clinical development activities.Cross-Functional Project ManagementDrive integrated project plans across Process Development, Formulation, Analytical Development, Regulatory CMC, Quality, and Supply Chain.Own timelines, milestones, budgets, and risk registers for assigned programs.Chair regular cross-functional meetings and ensure clear decision-making and accountability.Technical Oversight & Risk ManagementPartner with scientific teams to identify and mitigate CMC and manufacturing risks associated with bRo5 molecules.Track and coordinate risk-based development strategies, including enabling formulations and early manufacturability assessments.Ensure appropriate application of DoE, modeling, and platform technologies where relevant.External Partner & CDMO ManagementAct as the primary interface with external CDMOs, CROs, and formulation partners supporting bRo5 programs.Oversee tech transfer activities, development campaigns, and GMP manufacturing readiness.Coordinate issue resolution related to deviations, changes, and supply risks.Regulatory & Governance SupportCoordinate inputs for CMC regulatory submissions (IND/IMPD/CTA, NDA/MAA), ensuring consistency and technical accuracy.Support responses to health authority questions related to complex molecule development.Prepare materials for internal governance and portfolio review meetings.Required QualificationsMSc or PhD in Chemistry, Pharmaceutical Sciences, Chemical Engineering, or related discipline.5–10+ years of experience in CMC project management or technical development, with direct exposure to bRo5 molecules.Strong understanding of non-traditional small molecules, including challenges related to solubility, permeability, and bioavailability.Demonstrated ability to manage complex, cross-functional development programs in biotech, pharma, or CDMO environments.Solid knowledge of cGMP, ICH guidelines, and regulatory CMC requirements.Excellent communication and stakeholder management skills. #J-18808-Ljbffr
-
Project Manager
il y a 2 jours
Paris, France Quanta part of QCS Staffing Temps pleinProject Manager - Paris - 12-Month Contract Our client, a global (bio)pharmaceutical manufacturing organisation, is recruiting for a Project Manager to join them on their new expansion project. Based in a charming french location, this is on a contractual basis, and will involve significantly growing the sites capacity for the manufacture of Biologics....
-
Project Manager
il y a 5 jours
Paris, France Group-IPS Temps plein**Job Information**: Industry **Engineering** *** City **Paris** *** State/Province **Île-de-France** *** Country **France** *** Zip/Postal Code **75006** *** As a Project Manager for large capital expenditure industrial projects, you will be responsible for overseeing the planning, execution, and successful completion of complex industrial...
-
Project Manager
il y a 6 jours
Paris, France Euronext Temps pleinRole Summary The Project Manager will (i) coordinate and ensure delivery of projects in the Derivatives & Post-Trade department of Euronext, and (ii) support the formalisation of the project roadmap. Projects at Euronext are varied, such as a new product launch or expansion, technical migration, integration, regulatory change, or business protection. They...
-
Project Manager
il y a 2 jours
Paris, France ic resources Temps pleinWe are working with a ambitious company based in France, specialising in high-performance mixed-signal ASICs, who are seeking a Project Manager to oversee their ASIC development projects, ensuring they're completed on time, within scope, and budget. Responsibility Lead and manage ASIC development projects from initiation to closure. Define project scope,...
-
Project Manager
il y a 1 semaine
Paris, France SHEIN Temps plein**ABOUT US** SHEIN is a global fashion and lifestyle e-retailer committed to making the beauty of fashion accessible to all. We use on-demand manufacturing technology to connect suppliers to our agile supply chain, reducing inventory waste and enabling us to deliver a variety of affordable products to customers around the world. From our global offices, we...
-
Project Manager
il y a 5 jours
Paris, France Entrust Temps pleinJoin us at Entrust At Entrust, we’re shaping the future of identity centric security solutions. From our comprehensive portfolio of solutions to our flexible, global workplace, we empower careers, foster collaboration, and build solutions that help keep the world moving safely. Get to Know Us Headquartered in Minnesota, Entrust is an industry leader in...
-
Project Manager
il y a 21 heures
Paris, France Euronext Temps pleinAre you ready to shape the future of capital markets? We are seeking a results‑driven Project Manager to join our Derivatives & Post‑trade team in Paris. Responsibilities Project Management & Delivery: Manage end‑to‑end projects in line with Euronext's Project Management methodology. Plan, coordinate and deliver complex projects from initiation to...
-
Project Manager
il y a 2 jours
Paris, France Geotab Temps plein**Who we are**: Geotab ® is a global leader in IoT and connected transportation and certified "Great Place to Work." We are a company of diverse and talented individuals who work together to help businesses grow and succeed, and increase the safety and sustainability of our communities. Geotab is advancing security, connecting commercial vehicles to the...
-
Project Manager
il y a 24 heures
Paris, France Euronext Temps pleinOverviewAre you ready to shape the future of capital markets? We're seeking a results-driven Project Manager to join our Derivatives & Post-trade team in Paris.You will be primarily responsible for: Project Management & Delivery Manage end-to-end projects in line with Euronext's Project Management methodology Plan, coordinate and deliver complex projects...
-
Project Manager
il y a 3 jours
Paris, France DXC Technology Temps pleinJob Description:Essential Job Functions:• Manage and lead a portfolio of projects, ensuring adherence to scope, schedule, and budget.• Collaborate with project teams to define clear project objectives and deliverables.• Monitor project progress, identify and manage issues and risks, and implement corrective actions.• Assist in resource allocation and...
