Postdoctoral Research Fellow in Gut-Liver On-Chip

il y a 2 semaines

GifsurYvette, Île-de-France Servier Temps plein
Join Our Team as a Postdoctoral Research Fellow in Gut-Liver On-Chip

We are a human-sized, international, and independent pharmaceutical company governed by a Foundation. Our unique model is our pride, but above all, it allows us to fully serve our vocation: "Committed to therapeutic progress for the benefit of patients." Today, we are a global leader in cardiology, and we have chosen to become a focused and innovative player in oncology by 2030, targeting difficult-to-treat cancers and dedicating over 70% of our R&D budget to this area. This challenge is pursued in parallel with the development of our generic activity to provide access to quality care for all, at a lower cost.

We are 21,900 passionate people from over 50 nationalities, driven by an entrepreneurial spirit. Every day, we move forward with and for patients, with and for our teams, driven by the desire to care, to dare, to develop, and to engage to be useful to those who need it.

Mission:

  • Establish a physiologically relevant in vitro 3D human gut-liver model.
  • Investigate the in vitro gut-liver pharmacokinetics, safety profile, and/or bioavailability of drugs in development using the developed model.
  • Publish at least one article on this model development and its validation.
  • The candidate will be involved in various initiatives related to the development of the use of Organ on a Chip. He/she will be offered to attend a congress or training abroad.
  • The candidate may be involved in the supervision of students.

Profile:

We are looking for a highly motivated and experienced postdoctoral researcher with a strong background in molecular biology, cellular biology, physiology, biomedical engineering, biophysics, or a related field.

  • Previous postdoctoral experience in human health, physiology, or bioengineering would be appreciated.
  • Experience in a field linked to human health, physiology, and/or bioengineering.
  • Cell culture basis (primary cells and cell lines: knowledge, maintenance, microscopy)
  • In vitro experimentation. Experience with microphysiological systems / organs-on-chip is appreciated.
  • Pharmacokinetic and/or toxicologic knowledge is appreciated.
  • Experience with human hepatocytes and/or gut culture is appreciated.
  • Knowledge in liquid chromatography coupled to mass spectrometry, immunofluorescence, histology, enzymology assays, transporter activity assays, or RT-qPCR are a plus.
  • Rigorous, with analytical thinking and curiosity.
  • Ability to work within a team environment – team spirit.
  • Ability to work independently.
  • Good communication skills (English written/spoken fluently – French is a plus but not required)
  • Faculty to adapt and open-mindedness.
  • Sharing spirit / Transparency.

We are committed to equality of opportunities and the development of talents in all their diversity. We value experience as much as the desire to engage daily to be useful to therapeutic progress for the benefit of patients. If you recognize yourself in this offer and these few lines, seize this opportunity to meet us.

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