Research Scientist

Il y a 2 mois


SoisysurSeine, Île-de-France Kyron Temps plein

About the Role

We are seeking a highly skilled Research Associate to join our team at Kyron. As a Research Associate, you will play a key role in the engineering of mammalian cell lines and analysis of therapeutic proteins produced in engineered cell lines.

Key Responsibilities

  • Design and implement strategies for generating stable mammalian cell lines expressing therapeutic proteins of interest
  • Optimize expression of genes of interest in mammalian cells by testing different promoters, UTRs, and other regulatory elements
  • Purify recombinant proteins produced in mammalian cells and prepare high-quality samples for downstream analysis
  • Characterize purified therapeutic proteins using a range of techniques, including quantification, western blotting, activity assays, stability assays, and protein secondary structure determination
  • Contribute to the development of new cell lines and expression systems for the production of therapeutic proteins
  • Collaborate with colleagues to achieve project goals and objectives

Requirements

  • PhD in glycobiology, cell and molecular biology, biochemistry, biological engineering, or a related field
  • Experience working with glycoproteins and/or the protein secretory pathway
  • Excellent basic molecular biology techniques, including mammalian cell culture, transfections, bacterial cloning, PCR, and qPCR
  • Fluency in English
  • Strong communication and teamwork skills

Desirable Skills

  • Postdoctoral studies
  • Experience in a biotech/pharmaceutical company
  • Prior expertise with CHO or HEK cell lines
  • Patent inventor
  • Experience working with plant and yeast recombinant expression systems
  • Strong bioinformatic skills

About Kyron

Kyron is a fast-growing biotechnology company dedicated to the development of innovative therapeutic proteins. We are committed to creating a dynamic and collaborative work environment that fosters scientific excellence and innovation.


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