Research Scientist
Il y a 2 mois
About the Role
We are seeking a highly skilled Research Associate to join our team at Kyron. As a Research Associate, you will play a key role in the engineering of mammalian cell lines and analysis of therapeutic proteins produced in engineered cell lines.
Key Responsibilities
- Design and implement strategies for generating stable mammalian cell lines expressing therapeutic proteins of interest
- Optimize expression of genes of interest in mammalian cells by testing different promoters, UTRs, and other regulatory elements
- Purify recombinant proteins produced in mammalian cells and prepare high-quality samples for downstream analysis
- Characterize purified therapeutic proteins using a range of techniques, including quantification, western blotting, activity assays, stability assays, and protein secondary structure determination
- Contribute to the development of new cell lines and expression systems for the production of therapeutic proteins
- Collaborate with colleagues to achieve project goals and objectives
Requirements
- PhD in glycobiology, cell and molecular biology, biochemistry, biological engineering, or a related field
- Experience working with glycoproteins and/or the protein secretory pathway
- Excellent basic molecular biology techniques, including mammalian cell culture, transfections, bacterial cloning, PCR, and qPCR
- Fluency in English
- Strong communication and teamwork skills
Desirable Skills
- Postdoctoral studies
- Experience in a biotech/pharmaceutical company
- Prior expertise with CHO or HEK cell lines
- Patent inventor
- Experience working with plant and yeast recombinant expression systems
- Strong bioinformatic skills
About Kyron
Kyron is a fast-growing biotechnology company dedicated to the development of innovative therapeutic proteins. We are committed to creating a dynamic and collaborative work environment that fosters scientific excellence and innovation.
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