Postdoctoral Researcher: Formulation and Characterization of Emulsions and Hydrogels

il y a 3 jours


Nanterre, Île-de-France IRSN Temps plein
Job Description

The postdoctoral researcher will contribute to the formulation and physicochemical characterization of emulsions and hydrogels made of hydrophilic or amphiphilic chelating agents at IGPS, and to the assessment of their effectiveness in decontaminating damaged skin or wounds exposed ex vivo to actinides, cesium, or cobalt isotopes using automated Franz diffusion cells systems, at IRSN.

Responsibilities
  • Implement different formulation methods to incorporate chelating agents in pharmaceutical forms relevant for topical applications on damaged skin or wounds;
  • Characterize the granulometry, rheological properties, and stability of the pharmaceutical forms;
  • Perform ex vivo skin diffusion studies of the radioisotopes through murine, porcine, or human skins using Franz cells with or without decontamination treatments;
  • Analyze the radionuclides in the different compartments and samples using analytical techniques;
  • Analyze the results of experiments and write articles for publication in peer-reviewed journals, as well as research reports for internal or external purposes;
  • Prepare and present talks and poster presentations at internal and external seminars and meetings when requested and approved.
Requirements
  • PhD degree in physicochemistry, pharmaceutical technology, pharmacology, biology, chemistry, or a relevant discipline from a recognized university;
  • Comprehensive background and experience in one or more of the following areas: colloids, (nano)emulsions, hydrogels, or dispersed systems formulation and characterization;
  • Experience in skin physiology, radiobiology, radiotoxicology, in vitro skin diffusion study, Franz diffusion cells systems, or active ingredients analytical methods will be considered as an asset;
  • Demonstrated ability to publish research results as a lead author in peer-reviewed scientific literature;
  • Effective communication skills to present results of research as demonstrated by a record of conference or other oral presentations in English;
  • Demonstrated high organization skills, interpersonal skills, and ability to work as part of a multidisciplinary and dynamic team.


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