Thyroid Organoid Researcher
il y a 3 semaines
We are seeking a highly skilled researcher to join our team at the Institute for Radiological Protection and Nuclear Safety (IRSN). The successful candidate will be responsible for analyzing the response of human normal thyroid organoids to ionizing radiation.
Key Responsibilities:
- Develop and implement protocols for the analysis of thyroid organoids exposed to low doses of radiation
- Conduct experiments to explore the oxidative status of organoids after exposure, including exploration of key signaling pathways, mitochondrial function, and reactive oxygen species production
- Collaborate with the laboratory of T. Pourcher to develop metabolomic approaches
- Maintain the long-term culture of thyroid organoids and monitor their response to radiation over time
Requirements:
- PhD in molecular and cellular biology
- Experience in cell culture and knowledge of molecular mechanisms of cellular response to genotoxic stress
- Ability to present research findings at scientific conferences and to administrative authorities
Working Conditions:
Occasional telework
Additional Information:
The position will be located at the IRSN in Fontenay-aux-Roses, France. Salary will be based on qualifications and experience according to the IRSN salary grid. Applications will be considered until the position is filled.
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Thyroid Organoid Radiation Response Analyst
il y a 4 semaines
Nanterre, Île-de-France IRSN Temps pleinJob Title: Analysis of Human Normal Thyroid Organoids Response to Ionizing RadiationJob Summary:We are seeking a highly motivated and experienced researcher to join our team at the Institute for Radiological Protection and Nuclear Safety (IRSN) in France. The successful candidate will be responsible for analyzing the response of human normal thyroid...
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Nanterre, Île-de-France IRSN Temps pleinScientific ContextIonizing radiation exposure to the thyroid gland is a recognized risk factor for cancer development, particularly at high doses. However, the impact of low-dose exposure on thyroid organoids remains unclear. To address this knowledge gap, we are seeking a researcher to investigate the effects of ionizing radiation on human thyroid...
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Thyroid Organoids Radiation Response Analyst
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Nanterre, Île-de-France IRSN Temps pleinMissionScientific contextExposure to ionizing radiation during childhood is a recognized risk factor for thyroid cancer development. However, the impact of low doses on public health remains unclear. To address this question, we are developing an organoid model of human normal thyroid tissue, which reproduces the 3D organization of thyroid follicles and...
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Scientific Researcher
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Nanterre, Île-de-France IRSN Temps pleinMissionScientific contextExposure to ionizing radiation (IR) during childhood is a recognized risk factor for the development of cancers. However, the impact of low doses on public health remains unclear. To address this question, we are developing an organoid model of human normal thyroid tissue, which reproduces the 3D organization of thyroid follicles and...
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Scientist for Thyroid Organoids Response Analysis
il y a 1 semaine
Nanterre, Île-de-France IRSN Temps pleinScientific ContextExposure to ionizing radiation during childhood is a recognized risk factor for thyroid cancer development. However, the impact of low-dose radiation on thyroid health remains unclear. To address this knowledge gap, we are developing an organoid model of human normal thyroid tissue that reproduces the 3D organization of thyroid...
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Nanterre, Île-de-France IRSN Temps pleinJob DescriptionScientific ContextIonizing radiation exposure to the thyroid gland during childhood has been identified as a risk factor for cancer development. However, the impact of low-dose exposure on public health remains unclear. To address this knowledge gap, we are developing an organoid model of human normal thyroid tissue, which reproduces the 3D...
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Nanterre, Île-de-France IRSN Temps plein\t\tMission\tScientific Context\tThyroid exposure to ionizing radiation (IR) during childhood, following radioactive iodide contamination or external exposure, is a recognized risk factor for the development of cancers, as epidemiology studies have shown. However, the risk decreases with the dose, and the frequency of spontaneous thyroid cancers increases...
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Nanterre, Île-de-France IRSN Temps pleinMissionScientific ContextThyroid exposure to ionizing radiation during childhood is a recognized risk factor for the development of cancers. However, the risk decreases with the dose, and statistical epidemiological methods are no longer applicable. To address this knowledge gap, we are developing an organoid model derived from human normal thyroid tissue,...
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Nanterre, France IRSN Temps pleinMissionScientific contextThyroid exposure to ionizing radiation (IR) during childhood, following radioactive iodide contamination or external exposure is a recognized risk factor for the development of cancers by epidemiology studies, but for thyroid doses above 50mGy. As the risk decreases with the dose and the frequency of spontaneous thyroid cancers...
