Postdoctoral Researcher in Molecular Biology and Microfluidics

il y a 4 semaines


Paris, Île-de-France PSL Université Paris Temps plein
Postdoctoral Researcher in Molecular Biology and Microfluidics - PSL Université Paris

Institution Overview

PSL Université Paris is a prestigious institution recognized for its excellence in higher education and research, contributing significantly to scientific advancements and innovation across various disciplines.

Research Focus

The research conducted at PSL Université Paris emphasizes the integration of physics, chemistry, and biology, fostering a collaborative environment that promotes groundbreaking discoveries. The laboratory directed by Prof. Andrew Griffiths specializes in droplet-based microfluidics, a cutting-edge technology that allows for the miniaturization of reaction volumes, enhancing the throughput of biological assays.

Project Overview

The focus of this research project is to investigate the dynamic characteristics of chromatin and transcriptional elements in relation to tumor evolution, particularly in the context of cancer treatment responses and the development of resistance mechanisms. Recent findings in triple-negative breast cancer (TNBC) have highlighted the complexity of chromatin states in models of acquired resistance.

The selected candidate will be engaged in pioneering droplet-based microfluidics techniques to simultaneously analyze histone modifications and RNA expression within individual cells, thereby advancing our understanding of cellular responses in cancer biology.

Candidate Profile

We are looking for a highly driven postdoctoral researcher with a robust background in molecular biology, particularly in techniques such as scChIP-seq and RNA-seq. Experience in microfluidics, cell biology, and bioinformatics will be considered advantageous.

Essential qualities include adaptability, independence, the capacity to collaborate within a multidisciplinary team, and strong interpersonal skills.



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