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Research Scientist in Bioanalysis by LC-MS/MS

Il y a 2 mois


SoisysurSeine, Île-de-France AB Science Temps plein
Job Title: Research Technician/Engineer in Bioanalyses by LC-MS/MS

AB Science is a pharmaceutical company dedicated to the development of innovative new drugs for human and veterinary medicine.

We are committed to professional equality between women and men and believe that employee diversity is a source of wealth and contributes to strengthening social cohesion.

Job Description:Key Responsibilities:
  • Develop and validate methods for the determination of small chemical molecules by Ultra High Performance Liquid Chromatography (UHPLC) coupled with LC-MS/MS tandem mass spectrometry.
  • Perform in vitro biology experiments to evaluate the physico-chemical and ADME properties of molecules from our medicinal chemistry laboratories, including solubility, pKa, LogP, LogD, permeability/carriers, metabolic stability, and plasma protein binding.
  • Analyze samples from in vitro biological experiments on a routine basis.
  • Routine analysis of biological samples from in vivo biological experiments, including determination of pharmacokinetic parameters and biomarker analysis.
  • Perform data quality control.
  • Write and re-read procedures.
  • Participate in the proper functioning of the laboratory and maintenance of equipment.
Requirements:
  • Scientific training in Analytical Chemistry or Biochemistry (bac+2/3 to bac+5).
  • Minimum of 2+ years of industrial or academic experience in Bioanalysis on a similar position.
  • Knowledge of LC-MS/MS and sample preparation, as well as experience in UHPLC analysis with mass spectrometry detection.
  • Proficient in scientific English and computer tools (Empower, Mass Lynx, Analyst, Mass Metasite).
  • Highly organized and able to work independently.
  • Ability to work on multidisciplinary projects.
Terms and Conditions:
  • Permanent contract (CDI, 35 hours/week).
  • Paris South area (Evry genopole, Campus 1) based post office.
  • Salary to be defined according to profile and experience.