Scientist I Cell Line Development

il y a 3 jours


Toulouse, France Evotec Temps plein

Scientist I Cell Line Development

Just-Evotec Biologics is looking for a scientist I to join a fast-paced, collaborative, and multidisciplinary team to develop expression systems for low-cost biotherapeutics manufacturing.

Responsibilities:

- Establish stable, clonal cell lines for the expression of therapeutic proteins
- Suggest process and sciences improvements to keep cell lines/processes competitive
- Ensure the compliance of the data/results by matching to the regulatory requirements
- Valorize the results by preparing protocols, reports and slides and presenting data and future plans at group and cross functional meetings
- Collaborate with partner groups across the Just organization in Toulouse and US, including Process & Product Design, Quality Control, Quality Assurance and Manufacturing to ensure an optimal development plan
- Provide technical expertise as functional leader to internal and external teams regarding cell line development, cell bank manufacturing and management
- Being part of client project team

Requirements:

- M.Sc. in Molecular and Cell Biology, Bioengineering/Biotechnology or related fields with 0-5 years of relevant experience, or Ph.D. with mínimal relevant experience
- Excellent English written and verbal communication skills, including the ability to communicate effectively over teleconference and web-based meetings
- Deep understanding of cell line generation mechanisms

Preferred Qualifications:

- Experience in cell line generation with mammalian cell lines such as CHO, HEK-293 and NS/0
- Experience in cell bank manufacturing
- Experience in Expression plasmid development and gene editing
- Knowledge in design of experiment
- Knowledge of regulatory guidance from the FDA and EMA for development of cell banks
- Knowledge of ICH, USP and Ph. Eur. as it relates to biologics development
- Good written and verbal French communication skills



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