Engineer F/m Integrating External Multi-sources

il y a 7 jours


Paris, France Inria Temps plein

Le descriptif de l’offre ci-dessous est en Anglais_

**Type de contrat **:CDD

**Contrat renouvelable **:Oui

**Niveau de diplôme exigé **:Thèse ou équivalent

**Fonction **:Ingénieur scientifique contractuel

**Contexte et atouts du poste**

**Within the framework of the PEPR SN SMATCH and in collaboration with the PreMeDICaL Inria team.**

This research project focuses on the integration of external multi-source data to enhance decision-making in clinical research. The first task involves selecting relevant external data by assessing the similarity, discordance, and heterogeneity of results from various sources. Divergence-based distances will be refined to measure concordance between posterior distributions, ensuring that differences in sample sizes across sources do not distort comparisons. Transformations will be applied to standardize distributions, enabling consistent and meaningful integration of information. This approach aims to effectively propagate combined knowledge and uncertainties to subsequent clinical phases.

The second task addresses the issue of research waste caused by interrupted clinical trials, which often lead to significant information loss and reduced statistical power. This project will develop statistical methods to mitigate these challenges, employing frequentist analyses, Bayesian inference, and the incorporation of synthetic and auxiliary data from external sources. By doing so, it aims to preserve valuable information and improve the reliability of results in both individually and cluster-randomized trials.

**Mission confiée**

**Collaborations**

**Responsibilities**

Mission 1: Design and develop innovative methods to improve existing models.

Mission 2: Translate into codes and software the innovative methods.

**Principales activités**

Main activities

  • Bibliography search of existing approaches;
  • Improving the coding and explanations of methods for selecting and incorporating external data;
  • Improving the coding and explanations of methods for coping information loss in halted clinical trials;
  • Participating in scientific articles writing;
  • Participating to conferences.

**Compétences**

Technical skills and level required

  • Advance knowled in mathematics (pure or applied)
  • R and/or Phyton coding

Languages

  • Fluent in English

Relational skills

  • Feel confortable to work in a team

**Avantages**

  • Subsidized meals
  • Partial reimbursement of public transport costs
  • Leave: 7 weeks of annual leave + 10 extra days off due to RTT (statutory reduction in working hours) + possibility of exceptional leave (sick children, moving home, etc.)
  • Possibility of teleworking and flexible organization of working hours
  • Professional equipment available (videoconferencing, loan of computer equipment, etc.)
  • Social, cultural and sports events and activities
  • Access to vocational training
  • Social security coverage

**Informations générales**

  • **Thème/Domaine**: Neurosciences et médecine numériques

Statistiques (Big data) (BAP E)

  • **Ville**: Paris
  • **Centre Inria**: Centre Inria de Paris
  • **Date de prise de fonction souhaitée**: 2025-02-01
  • **Durée de contrat**: 3 ans
  • **Date limite pour postuler**: 2025-01-06

**Consignes pour postuler**

**Sécurité défense**

Ce poste est susceptible d’être affecté dans une zone à régime restrictif (ZRR), telle que définie dans le décret n°2011-1425 relatif à la protection du potentiel scientifique et technique de la nation (PPST). L’autorisation d’accès à une zone est délivrée par le chef d’établissement, après avis ministériel favorable, tel que défini dans l’arrêté du 03 juillet 2012, relatif à la PPST. Un avis ministériel défavorable pour un poste affecté dans une ZRR aurait pour conséquence l’annulation du recrutement.

**Politique de recrutement**

Dans le cadre de sa politique diversité, tous les postes Inria sont accessibles aux personnes en situation de handicap.

**Contacts**

  • **Équipe Inria**: HEKA

- **Recruteur**

**A propos d'Inria**

Inria est l’institut national de recherche dédié aux sciences et technologies du numérique. Il emploie 2600 personnes. Ses 215 équipes-projets agiles, en général communes avec des partenaires académiques, impliquent plus de 3900 scientifiques pour relever les défis du numérique, souvent à l’interface d’autres disciplines. L’institut fait appel à de nombreux talents dans plus d’une quarantaine de métiers différents. 900 personnels d’appui à la recherche et à l’innovation contribuent à faire émerger et grandir des projets scientifiques ou entrepreneuriaux qui impactent le monde. Inria travaille avec de nombreuses entreprises et a accompagné la création de plus de 200 start-up. L'institut s'efforce ainsi de répondre aux enjeux de la transformation numérique de la science, de la société et de l'économie.



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