INTERNSHIP - Software development engineer - Biomedical applications

il y a 6 jours

Montreuil, Île-de-France 4Dcell Temps plein

Software development engineer -

Biomedical applications

Unlock the Future of Drug Discovery.

Join 4Dcell and become part of a pioneering French biotech on a mission to transform drug discovery and toxicology. We're engineers and biologists united by a single goal: to replace animal testing with intelligent, in vitro "organ-in-a-well" models that deliver unprecedented predictive power to drive tomorrow's therapies.

4Dcell has developed two flagship solutions: the SmartHeart Platform, which recreates human ventricular tissue in a standard 96-well plate, and the first-in-class SmartSphero Technology, enabling the generation of a wide range of organoids. 

You'll collaborate with leading biophysicists, engineers, and biologists to tackle the toughest health challenges, from heart failure and immuno-oncology to pancreas and renal diseases. We combine ambition with a supportive, curiosity-driven culture.

Why intern with us?

  • Freedom and responsibility to structure and lead your own projects
  • Hands-on exposure to game-changing technologies
  • A team that values collaboration, growth, and fun
  • Membership in a high-energy, fast-growing team developing truly game-changing, high-tech products
  • The opportunity to navigate both a commercial start-up environment and an R&D scientific setting
  • Close collaboration with experts in technology, marketing, sales, application science and operations
  • Step into a role where your work accelerates drug discovery, improves patient outcomes, and builds a more ethical pharmaceutical future.

Context

4Dcell has developed a platform to produce 3D ring-shaped organoids

. The cells self-assemble in a contractile ring around a deformable central pillar. To assess the contraction of the tissues, a software based on image segmentation was developed to track the inner and outer rings of the tissues. You will contribute to the continued development and optimization of
SmartX 2.0

, focusing on improving segmentation accuracy, analysis speed, and expanding its capabilities. This is a high-impact internship, directly supporting the advancement of 3D cardiac tissue modeling.

Main Responsibilities

·
New Feature Integration:

Extend the software to support
fluorescence signal analysis

, allowing for dual-mode analysis (contraction + fluorescence intensity).

·
Software Optimization:

Improve precision and performance of the contraction analysis pipeline, including parameter tuning, image preprocessing, and signal processing.

·
UX & Speed Enhancements:

Redesign key components of the SmartX 2.0 interface and back-end for better usability, scalability, and speed.

·
Model Training & Evaluation:

Train and fine-tune image segmentation models on curated image datasets of organoid rings.

Candidate Profile

· Master's student in Engineering with a specialization in Software Engineering, Deep learning, or related field. OR Master's student in Software Engineering with knowledge in biology

· Solid programming skills in Python

· Experience with image processing, segmentation and machine learning libraries.

· Interest in biomedical applications.

· Strong autonomy

· Strong communication and listening skills: interactions with internal and external collaborators, to adapt the software to the clients' needs

· Bonus: Experience with GUI development (e.g., PyQt, Tkinter) and bioimaging tools (ImageJ/Fiji, CellProfiler). Experience in signal processing appreciated.

Duration & Terms

  • 6-month internship, starting /February March 2026
  • Based in Montreuil, with partial remote work possible

Legal internship stipend 650€ + partial transport reimbursement

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