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INTERNSHIP - R&D and Production project manager assistant

Unlock the Future of Drug Discovery.

Join 4Dcell and become part of a pioneering French biotech on a mission to transform drug discovery and toxicology. We're engineers and biologists united by a single goal: to replace animal testing with intelligent, in vitro "organ-in-a-well" models that deliver unprecedented predictive power to drive tomorrow's therapies.

4Dcell has developed two flagship solutions: the SmartHeart Platform, which recreates human ventricular tissue in a standard 96-well plate, and the first-in-class SmartSphero Technology, enabling the generation of a wide range of organoids.

You'll collaborate with leading biophysicists, engineers, and biologists to tackle the toughest health challenges, from heart failure and immuno-oncology to pancreas and renal diseases. We combine ambition with a supportive, curiosity-driven culture.

Why intern with us?

  • Freedom and responsibility to structure and lead your own projects
  • Hands-on exposure to game-changing technologies
  • Apply marketing skills on a new, growing, exciting and revolutionary market
  • A team that values collaboration, growth, and fun
  • Membership in a high-energy, fast-growing team developing truly game-changing, high-tech products
  • The opportunity to navigate both a commercial start-up environment and an R&D scientific setting
  • Close collaboration with experts in technology, marketing, sales, application science and operations
  • Step into a role where your work accelerates drug discovery, improves patient outcomes, and builds a more ethical pharmaceutical future.

Context

Within our R&D & Production team, you will work hands-on with experimental protocols to characterize cardiac pathology models and the manufacturing of 2D or 3D cell culture systems for cardiovascular disease or oncology research.

Main Responsibilities

Market Survey

  • Gather and analyze market trends and needs for cardiac disease models
  • Identify competitor products and gaps in current offerings
  • Provide recommendations to guide future disease-model development

Executing Design of Experiments (DoE)

  • Prepare culture media and reagent dilutions
  • Seed cells at defined densities according to the DoE matrix
  • Record all steps and observations in the lab notebook (LIMS/Excel)

Data Processing & Analysis

  • Import raw metrics (viability, marker expression, contractility)
  • Create summary tables and plots to compare conditions
  • Draft concise experimental summaries with actionable conclusions

3D Cell Culture

  • Set up spheroids, hydrogels
  • Conduct immunofluorescent staining and confocal imaging

2D/3D Cell Culture System Production

  • Support the Production Manager with various production tasks

Deliverables

  • Market survey to support decision-making for future disease model development
  • Complete experimental records (DoE details, raw results, observations)
  • Analyzed datasets with clear graphical outputs
  • Updated operational protocols
  • Brief reports for each experimental campaign

Environment & Tools

  • Equipment: CO₂ incubators, laminar-flow hoods, confocal microscope
  • Software: LIMS/Excel, GraphPad Prism, R or basic Python notebooks
  • Techniques: DoE, 2D & 3D cell culture, immunofluorescence

Candidate Profile

  • Master's student in Biology, Biotechnology or Biomedical Engineering
  • Hands-on experience with cell culture (2D and/or 3D)
  • Comfortable with data entry and analysis
  • Organized, experimentally rigorous and proactive

Good technical English

Duration & Terms

  • 6-month internship, starting January or February 2026
  • Based in Montreuil
  • Legal internship stipend + partial transport reimbursement