Senior USP/DSP engineer

il y a 2 semaines


BaillyRomainvilliers, Île-de-France InnoBioMil Temps plein

Founded in 2019 in Bailly-Romainvilliers near Paris, InnoBioMil supplies national and international clients with
premium cell-culture media and feeds
. All products are manufactured in a cleanroom environment in full compliance with the strictest biopharmaceutical regulatory standards.

InnoBioMil is seeking a highly motivated and enthusiastic candidate for the position of:
Senior Bioprocess Engineer.

The ideal candidate will have solid experience in biotechnology.

Main Responsibilities

  • Lead the development of
    fed-batch cell culture processes
    at the R&D scale, with effective transfer and optimization toward pilot scale.
  • Supervise, train, and support a team of engineers specialized in
    cell-culture media formulation
    , ensuring scientific rigor and experimental reproducibility.
  • Design, formulate, and optimize
    chemically defined (CD), animal-component–free (ACF), or custom cell-culture media
    , integrating metabolic modeling and multiparametric analysis approaches.
  • Identify, specify, and integrate
    bioproduction equipment
    , including media-preparation systems, bioreactors of various technologies, PAT sensors, and automation tools.
  • Develop, execute, and oversee experimental programs covering
    intermediate cultures (shake flasks)
    and
    benchtop bioreactors
    , with in-depth monitoring of critical process parameters (CPP) and critical quality attributes (CQA).
  • Implement and continuously improve
    analytical methods and PAT tools
    (online viability, Raman, metabolomics) to strengthen real-time monitoring and enhance advanced process control.
  • Implement and develop
    analytical methods for assessing quality profiles
    of biotherapeutic products (e.g., biosimilars, recombinant proteins).

Required Profile:

  • PhD in biochemical engineering, bioprocess engineering, or bioproduction
    , with a minimum of 3 years of relevant experience, ideally in an industrial environment (biotech, pharma, CDMO).
  • Experience in working with CHO cells and on recombinant proteins is
    mandatory
    .
  • Proven experience in
    bioreactor operation
    (from lab to pilot scale) and process optimization.
  • Strong knowledge of
    cell metabolism
    .
  • Experience in
    downstream processing (DSP)
    and quality-attribute profiling is desirable.
  • Ability to solve complex scientific challenges using
    scientific literature, technology monitoring, and critical thinking
    .
  • Team-oriented mindset, scientific curiosity, and enthusiasm for innovation and the growth of a developing company.
  • Excellent
    written and spoken communication skills in English
    .

Please apply directly or by sending your CVs to with the headline: "senior USP/DSP engineer position".


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