Scientist

Il y a 18 heures

Paris, France Cyllene Therapeutics Temps plein 44 000 € Contrat

As Scientist you will conduct epigenetics/epigenomics experiments for extending the knowledges of the HERMES vectors to develop new DNA medicine products.

You will drive hands-on execution on these projects. The role advances novel therapeutic products from early discovery through preclinical readiness in a fast-paced, collaborative startup environment. This position requires deep technical expertise, strategic thinking, and the ability to operate independently.

Directly reporting to the Principal Scientist, you will:

  • Manage the design, optimization, production, and characterization of new nrHSV-1 viral vectors

  • Design, execute and optimize a variety of laboratory experiments independently in vectorology, molecular and cellular biology, and epigenomics including but not limited to bulk and single cell RNA-seq, ATAC-seq ChIP-seq, Hi-C

  • Analyze data, interpret results, and draw conclusions

  • Independently author, review, and ensure the quality and regulatory compliance of scientific documentation, maintaining comprehensive documentation standards and full experimental traceability. Prepare and review scientific reports, technical documentation, and patent applications

  • Collaborate closely within the Research team and the other teams

  • Contribute to technical discussions, innovation activities, and continuous improvement of the HERMES platform

  • Apply agile ways of working to effectively prioritise activities, make strategic decisions, and adapt to changing business and project needs

  • Present scientific results and scientific monitoring insight to cross-functional teams, supporting knowledge sharing and strategic decision-making

  • Present posters at scientific conferences.

Preferred experience

  • PhD in Epigenetics, Molecular Biology, Virology, or a related discipline

  • Professional experience in industry experience

  • Strong experiences in Epigenetics, Epigenomics, as well as genomics and transcriptomics, proven track record in epigenetics and discovery research

  • Knowledge of quality compliance, scientific documentation standards and experimental traceability frameworks, with a strong commitment to data integrity, quality systems, and regulatory compliance

  • Expertise in AAV or HSV-based gene delivery or related viral vector systems is highly preferred

  • Communication skills to present results to colleagues during cross-functional team meetings

  • English (spoken and written)

Recruitment process

  • Interview with the Manager - Principal Scientist (1 hour)

  • Interview with the VP Research (30 minutes)

  • Interview with the CEO (30 minutes)