Cell Biology Scientist
il y a 3 semaines
Prise de poste : 01/03/2023 Docteurs Paris
Nombre de postes non défini CDI À négocier
**Description du poste et des missions**:
**Alaya.bio **est une jeune société de biotechnologie qui développe des solutions thérapeutiques innovantes pour les patients dans le domaine de l’immuno-oncologie et des maladies génétiques.
Le poste est basé à Paris.
**Vos missions**
- Développer et mettre en œuvre des méthodes et des tests appropriés pour sélectionner, caractériser et optimiser un composant de la plateforme thérapeutique développée par l’entreprise.
- Contribuer à la validation de l’efficacité de notre plateforme thérapeutique.
- Concevoir et exécuter des plans expérimentaux en étroite collaboration avec les différents experts de l’entreprise.
- Participer à la gestion opérationnelle du laboratoire : gestion des achats, maintenance des équipements, respect de la réglementation et des règles d’hygiène et de sécurité en place dans l’entreprise.
- Rédaction de documents techniques (modes opératoires), de protocoles et de rapports d’études.
- Participation à la dissémination des résultats scientifiques de l’entreprise (brevets, articles scientifiques, communications dans des conférences internationales).
**Votre profil**
- Doctorat en biologie moléculaire et cellulaire, immunologie ou équivalent.
- Forte expertise en cytométrie en flux multiparamétrique, en manipulation de cellules primaires (isolement et caractérisation de PBMCs) et en essais fonctionnels sur cellules (ciblage, activation, internalisation, cytotoxicité).
- Expérience dans la sélection et l’ingénierie de biomolécules ayant des propriétés de liaison (interaction sur protéines recombinantes et sur cellules, ELISA, dosage multiplex de cytokines, identification d’épitopes, analyse BLI/SPR des interactions protéine-protéine).
- Des connaissances supplémentaires en biologie moléculaire (PCR préparative, conception et préparation d’une banque d’ADN aléatoire) et le développement de tests cellulaires à haut débit sont un atout.
- Un niveau d’anglais avancé est requis pour ce poste, en raison des enjeux internationaux du développement de l’entreprise.
- Maîtrise des outils informatiques
**Candidature**
Il vous suffit de nous envoyer votre CV accompagné d’une lettre de motivation sur notre portail de recrutement.
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