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QSP Modeling intern

il y a 2 semaines


Lyon, France Nova In Silico company Temps plein

Nova In Silico is a health tech company that develops an in silico clinical trial platform jinkō to simulate drug efficacy and optimize clinical development using virtual patients and disease modeling. As an innovative company, we offer a dynamic work environment distinct from larger, established organizations. Interns will gain significant responsibilities and benefit from a steep learning curve, supported by a highly motivated team. Learn more at www.novainsilico.ai .BackgroundNova In Silico is a pioneer in the field of in silico clinical trials, which are poised to become an industry standard as regulators now see Modeling and Simulations (M&S) as a strategic priority. Each commercial project is aimed to unlock the potential of M&S and allow our biotech and pharma partners to accelerate and de-risk the R&D of new therapies by establishing their clinical benefits upstream of human trials. To predict drug efficacy, Nova In Silico creates and uses models with jinkō platform, an internal platform which brings together the modeling and simulation expertise of the company.ObjectivesInvestigate and develop disease or treatment models to fulfill partner requirements, thereby contributing to the R&D process.You are :team player, a good listener, and an effective communicator : Join a growing multidisciplinary team of enthusiastic innovatorsCurious and proactive with a solid grounding in biology: Particularly in cell biology, molecular biology, and omics, to address real-life clinical issues.Autonomous and self-motivated with strong analytical and problem-solving skills: Find innovative solutions to science and engineering problemsEager to learn and use mathematical methods for the modeling of biological systems : Simulate virtual diseases and treatments with ODE, PDE, Monte-Carlo SimulationsWilling to explore and exploit large datasets and virtual populations: Apply machine learning, statistical analysis, and outliers detectionResponsive and capable of facing time-sensitive challenges: Project management with client-facing opportunities are awaiting youYou will :Contribute actively to the creation of in silico pathophysiological and treatment modelsParticipate in weekly and monthly project meetings and reportingAnalyze extensive real-world datasets and simulation resultsImpact the development of nova’s simulation platformMethodology and technical skills:We mainly use internal tools (jinkō platform) for creating the models, and R for result analysis.We are looking for people who know some of the following fields or are eager to learn and work with themMechanistic modeling, ODEs, PK-PDScientific computing and statistics (R, Python)Knowledge in biology, biochemistry and/or pharmaceutical sciencesKnowledge in machine learning and optimization techniques (e.g. SAEM, gradient descent)Knowledge in clinical trials and drug developmentA professional English level (written and oral) is required for this role #J-18808-Ljbffr