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Research Scientist
Il y a 2 mois
About the Role
We are seeking a highly skilled Research Associate to join our team at Kyron. As a Research Associate, you will play a key role in the engineering of mammalian cell lines and analysis of therapeutic proteins produced in engineered cell lines.
Key Responsibilities
- Design and implement strategies for generating stable mammalian cell lines expressing therapeutic proteins of interest
- Optimize expression of genes of interest in mammalian cells by testing different promoters, UTRs, and other regulatory elements
- Purify recombinant proteins produced in mammalian cells and prepare high-quality samples for downstream analysis
- Characterize purified therapeutic proteins using a range of techniques, including quantification, western blotting, activity assays, stability assays, and protein secondary structure determination
- Contribute to the development of new cell lines and expression systems for the production of therapeutic proteins
- Collaborate with colleagues to advance the company's research and development goals
Requirements
- PhD in glycobiology, cell and molecular biology, biochemistry, biological engineering, or a related field
- Experience working with glycoproteins and/or the protein secretory pathway
- Excellent basic molecular biology techniques, including mammalian cell culture, transfections, bacterial cloning, PCR, and qPCR
- Fluency in English and strong communication skills
- Ability to work independently and as part of a team
Preferred Qualifications
- Postdoctoral studies
- Experience in a biotech/pharmaceutical company
- Prior expertise with CHO or HEK cell lines
- Mass spectrometry experience
- Strong bioinformatic skills
About Kyron
Kyron is a fast-growing biotechnology company dedicated to advancing the field of glycobiology and developing innovative therapeutic proteins. We offer a dynamic and collaborative work environment, with opportunities for professional growth and development.