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Preclinical Research Scientist M/F

Il y a 3 mois


Bordeaux, Nouvelle-Aquitaine, France TreeFrog Therapeutics Temps plein
About Us

COMPANY

TreeFrog Therapeutics is a pioneering biotechnology firm dedicated to making cell therapies accessible to a vast number of patients through our innovative C-StemTM technology. This groundbreaking method allows for the large-scale cultivation and differentiation of stem cells, marking a significant advancement in the field. Since our establishment in 2018, we have successfully secured over €74 million in funding and are rapidly expanding with a talented team of over 150 professionals.

Role Overview

JOB DESCRIPTION

As a vital member of our preclinical team, you will report directly to the preclinical manager and work closely with technicians and researchers across various departments. Your contributions will be essential in managing all facets of preclinical operations, which include organizing and monitoring preclinical studies, overseeing bioanalytical processes, and managing samples. A background in toxicology studies, DMPK, and bioanalysis (such as histology) is highly advantageous.

KEY RESPONSIBILITIES

In collaboration with the R&D team and under the guidance of the preclinical manager, your responsibilities will encompass:

  • Participating in preclinical studies by planning, executing, collecting data, performing statistical analyses, preparing reports, and delivering presentations.
  • Supporting bioanalytical efforts related to preclinical studies.
  • Coordinating with preclinical CROs to ensure effective planning and execution of DMPK, bioanalytical, and toxicology studies, including managing budgets and financial processes.
  • Ensuring adherence to study protocols and monitoring compliance with ISO 9001:2015 certification and relevant regulations governing animal research.
  • Identifying potential risks and proposing timely solutions.
  • Facilitating communication and reporting of project activities in collaboration with the preclinical manager.
Candidate Profile

REQUIRED QUALIFICATIONS:

A PhD or equivalent in life sciences or a related discipline, preferably in neuroscience, regenerative medicine, or tissue engineering, along with several years of hands-on experience in preclinical studies. Familiarity with working alongside CROs is essential. Exceptional scientific writing skills are a must.

Experience in advanced therapy medicinal products (ATMP), particularly in gene and cell therapy, is desirable. Proficiency in conducting immunohistological studies and rodent surgeries (e.g., stereotaxic techniques) is a significant plus. Knowledge of statistical data analysis and project management will be beneficial.

A proven ability to collaborate effectively with cross-functional teams and external partners in a matrix environment is required. Understanding the roles of various disciplines such as pharmacology, ADME/PK, safety, and CMC in the non-clinical drug discovery process is essential.

SOFT SKILLS:

  • Self-motivated, organized, and detail-oriented with a critical and objective mindset.
  • Goal-driven, excellent communicator, and collaborative team player.
  • Ability to set operational priorities and achieve ambitious objectives.
  • Capable of leading, negotiating, and problem-solving while influencing the quality of deliverables.
  • Strong organizational skills with the ability to manage multiple tasks and prioritize effectively.
  • Proficient in project management tools.
  • Excellent written and verbal communication skills in English, with the ability to convey scientific information clearly and effectively.

At TreeFrog, we value individuals who embody our core principles (#Do, #Dust, #Be bold, #Commit, #Enjoy). We seek problem-solvers with a scientific curiosity, a willingness to step outside their comfort zones, and the ability to adapt quickly in a dynamic research environment.

Work Environment & Conditions

Contract Type: Permanent contract (CDI)

Salary: Based on experience