Immuno-oncology in Vivo Study Manager

**Immuno-Oncology **_**in vivo **_**Study Manager**

**Job offer #**:SM0524**

**Type**: Full time position, permanent contract

**Location**:Bordeaux, France

**You’re an accredited animal experimentalist with a passion for immune response mechanisms? You have experience with **_**in vivo **_**models for immuno-oncology ? You master flow cytometry and other platforms for ex vivo analysis ? The perspective of testing innovative cancer immunotherapies creates some excitement?**

Keep reading and apply

**About Explicyte**

**Explicyte is a preclinical and translational contract research organization specialized in immuno-oncology. **Our goal is to assist academics, biotechs and pharmas in the discovery of novel targets and novel cancer immunotherapies.

**With a team of 25, we’re a human-sized company**, which brings under the same roof cell biologists, immunologists, _in vivo _scientists, medical oncologists and bioinformaticians. **Focused on sponsors’ projects**, our activity also involves in-house R&D and external collaborations, which led to the publication of **25+ papers in high impact-factor journals.**

**Based in Bordeaux, our lab is located at the Bergonié Comprehensive Cancer Center**, where we work in close contact with medical oncology teams. We believe **Explicyte is a place to learn, grow, and have impact in the fight against cancer.**

**Your position**

To strengthen our _in vivo _preclinical activities, we are looking for an **experienced **_**in vivo **_**Immuno-Oncology Study Manager**, ready to take up with us the implementation of projects and their protocols, relevant for the **testing and development of novel immunotherapeutic modalities**.

In your role, you will be responsible for the technical and organizational **management of sponsors’ and in-house R&D **_**in vivo **_**studies**, from their implementation and performance to data analysis. You will timeously provide deliverables with respect to the project’s requirements and timelines.

You will closely interact with the _in vivo _team members. You will report to the Study Directors and CSO.

**Your skills & traits**
- **Ph.D - **or equivalent - in science and health-related field
- Accreditation in **animal experimentation level 1/2** is mandatory, ethical standards and regulations
- **Deep knowledge** and **mastery** of preclinical **tumor-bearing mouse models**
- **Expertise** in **tissue collection **and processing for **flow cytometry-based analysis**
- Knowledge in the fields of **tumor immunology and cancer therapies**
- Minimum **1-2 years’ experience in **_**in vivo**_preclinical development in a health industry: Pharma, Biotech, CRO
- **Project management** experience (from planning to closing projects)
- **Excellent diligence**
- **Strong interpersonal **& **organizational** skills
- **Ability** to **easily adapt** to changing priorities and challenges
- **Enthusiasm, curiosity, and integrity**

**Your missions & responsibilities**
- **Provide draft protocols **according to the proposed scientific and experimental strategies
- **Implement studies**:

- relying on undeniable organizational skills - according to their design and established schedules
- **Manage and perform**:

- diligently - _in vivo _and _ex vivo _experiments
- **Tumor cell line culture **and maintenance
- Mastery of **anesthesia and surgical gestures**
- **Tumor cell inoculation **(subcutaneous, intradermic, intracranial, mammary fat pad, intrasplenic, etc.)
- _**In vivo **_**monitoring**: tumor growth (physical, bioluminescence), body weight and survival, tolerability evaluation
- Mastery of neuro-oncology related _in vivo _protocols and models is a plus
- **Treatment administration **(oral, intraperitoneal, intravenous, intratumoral)
- **Sampling of biological tissues **(blood, tumor, lymph nodes, organs)
- _**Ex vivo **_**processing **of collected samples for immune or tumor cell isolation, or for further analyses (FACS, ELISA )
- **Capture, analyze and compile data**, including quality controls
- **Ensure accuracy and completeness of study documentation **and timely provide study deliverables
- **Write and submit animal referrals **for ethical committee approval
- **Write internal protocols **and standard operating procedures

Type d'emploi : Temps plein, CDI
Statut : Cadre

Rémunération : 25 000,00€ à 40 000,00€ par an

Avantages:

- Crèche d'entreprise
- Prise en charge du transport quotidien

Programmation:

- Du lundi au vendredi
- Travail en journée

Lieu du poste : En présentiel