Specialist, Lc-ms Analytical Development

**DNA Script** Our clean, efficient Enzymatic DNA Synthesis (EDS) technology, implemented on a benchtop instrument (the SYNTAX), accelerates innovation in life science and biotechnology through the decentralization of rapid, on demand and high quality DNA synthesis. Our approach builds upon nature's billions of years of evolution in enzymatically synthesizing DNA, setting new standards for assembling nucleic acids to accelerate scientific discovery and DNA/RNA production in disciplines with profound impacts upon humanity. DNA Script has a broad stable of high quality investors and is capitalized to continue its progress to full commercialization of the technology and products. We are building an organization across our two sites, in Paris and San Francisco, with the talent, skills and attitude to achieve our mission: to unlock the power of "DNA-write". This is an opportunity for a dynamic individual to join an international and highly skilled team, and to make significant contributions to commercializing a technology with far-reaching potential across the biological sciences and beyond. **We're Hiring: LC-MS Analytical Development Specialist | Shape the Future of Biotech** **Location**: Le Kremlin-Bicêtre **Type**: Full-time | Permanent **Department**: R&D - Analytical Development Are you passionate about mass spectrometry and biotech innovation? Do you thrive in a collaborative, fast-paced environment where your expertise makes a real impact? We're looking for a **LC-MS Analytical Development Specialist** to become our go-to expert in Mass Spectrometry and help drive forward cutting-edge analytical solutions. **About the Role**: As our in-house LC-MS expert, you'll lead **analytical development projects** centered on oligonucleotide analysis and other biomolecules, using state-of-the-art UPLC/UV, UPLC/MS (SQ, Q-ToF), and capillary electrophoresis systems. Your work will directly support the development of novel therapeutics and tools for the life sciences. This is a highly visible role within the company—one where your technical leadership will contribute not just to project success, but to the **standardization, innovation, and scalability** of our analytical practices. **What You'll Do**: - Lead the **development and validation** of new analytical methods (sample prep, UPLC/MS, etc.) and improve existing ones. - Manage **oligonucleotide sample analysis**, collaborating closely with R&D teams to interpret multi-technique results. - Take part in **routine and high-throughput analyses**, supporting projects across the company. - Drive **method transfer** to QC and ensure robustness for future scale-up. - Own instrument performance: maintenance, qualification, SOPs, logbooks, and system suitability testing. - Author high-quality **protocols and technical reports**, and contribute to scientific reviews and continuous learning. - Promote **cross-team collaboration** and act as an analytical science ambassador within the organization. **What We're Looking For**: **Must-Haves**: - MSc or equivalent in Analytical Chemistry, Biochemistry, or related field. - **5+ years' experience** in analytical development using **LC/MS** (low and high resolution) on biomolecules. - Deep expertise in **UHPLC** and **mass spectrometry data analysis**, including software tools. - Strong interpersonal and communication skills - French and English proficiency required. - Self-motivated and team-oriented with a hands-on, proactive mindset. **Nice-to-Haves**: - PhD in Analytical Chemistry - Industry experience (biotech, pharma, start-up environments) - Familiarity with **automation, SPE, and liquid handling robotics** **Why Join Us?**: - Work with **top-tier scientists** in a high-growth, mission-driven biotech company - Collaborate in a **supportive and intellectually curious team** - Be a **key player** in setting standards and innovating analytical methods - Access to the latest technologies in analytical instrumentation - Competitive compensation and a dynamic work culture **Ready to make your mark?