Engineer in Immunology
il y a 2 semaines
Engineer in Immunology (F/M) at Institut Curie Join to apply for the Engineer in Immunology (F/M) role at Institut Curie. Overview Institut Curie is a leading institution in cancer research and treatment, bringing together a Hospital Group and a Research Center with over 1,000 employees and a strong international presence. The Research Center’s mission is to advance fundamental research and translate scientific discoveries into improved cancer diagnosis, prognosis, and therapies, ensuring a seamless continuum from basic research to innovation dedicated to serving patients. About Us The Innate Immunity in Physiology and Cancer team is part of the Immunity and Cancer Unit (INSERM U932) at Institut Curie. Our primary goal is to uncover and characterize novel immune defense mechanisms in mammals, with a particular focus on innate immunity. Current research explores immune proteins conserved between bacteria and humans, in collaboration with Aude Bernheim’s team at Institut Pasteur, and builds innovative immunotherapies with translational researchers and clinicians. The Poirier team is supported by an ERC Starting Grant and a grant "Impact Santé" from France 2030. Project: An Innovative Immunotherapy of Lupus Innate immune mechanisms protect mammals against pathogens and contribute to tumor surveillance. Recent studies have shown that a subset of mammalian innate immune proteins, including those in humans, originate from bacterial defense systems. Our work demonstrates that exploring evolutionary conservation of immunity is a powerful strategy to uncover novel immune proteins in eukaryotes. Recently, we identified a previously unknown human immune protein, SIRal, which plays a pivotal role in the Toll-like receptor (TLR) signaling pathway of innate immunity. We are now launching a translational project to investigate the role of SIRal in human disease. Autoimmune disorders such as systemic lupus erythematosus (SLE) involve aberrant TLR-driven innate immune activation. In this project, we aim to determine whether SIRal represents a viable therapeutic target in lupus and related autoimmune conditions. The successful candidate will join this research program alongside a research engineer from the team, performing cell biology approaches and extensive studies in mouse models of autoimmunity. References F. Rousset, Trends Immunol. 44, 945–953 (2023). D. Bonhomme et al., Science. 389, eadr8536 (2025). Candidate Profile Training: Masters and PhD in Life Sciences are welcome to apply. Scientific skills: Experience in vivo experimentation is required. Language skills: English, oral and written. Transferable skills: ability to work in a team, excellent communication skills including oral presentations to specialized and non-specialized audiences. Contract Information Type of contract: Fixed‑term contract. Starting date: To be discussed. Duration: 12 months renewable. Working time: full time. Remuneration: according to the current grids. Benefits: Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance. Location: Paris, France. Contact Send your CV and letter of motivation. Publication date: 15/12/2025. Deadline for application: 04/01/2026. Equal Opportunity Statement Institut Curie is an inclusive, equal opportunity employer and is dedicated to the highest standards of research integrity. https://euraxess.ec.europa.eu/sites/default/files/brochures/eur_21620_en-fr.pdf ', #J-18808-Ljbffr
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Immunology Engineer for Translational Lupus Research
il y a 2 semaines
Paris, France Institut Curie Temps pleinA leading cancer research institute in Paris is seeking an Engineer in Immunology to join a team exploring immune defense mechanisms and developing innovative therapies for autoimmune diseases. The successful candidate will have a Masters or PhD in Life Sciences, experience in in vivo experimentation, and excellent communication skills. This full-time...
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il y a 2 semaines
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il y a 1 semaine
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Scientific Support Specialist, Immunology
il y a 3 jours
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il y a 2 semaines
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Evidence Generation Lead Immunology
il y a 2 semaines
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