Postdoctoral Researcher in Spatial Transcriptomics of Vascular Ageing Conditions

il y a 3 semaines


St Étienne, Auvergne-Rhône-Alpes, France Institut Mines-Télécom Temps plein

Job Environment:

Institut Mines-Télécom is a leading public group of engineering and management Grandes Écoles in France, consisting of eight public graduate Grandes Écoles and two subsidiary graduate schools. The group leads and develops a rich ecosystem of partner schools, economic, academic, and institutional partners, key players in education, research, and economic development.

Mines Saint-Étienne, a graduate school of the Institut Mines-Télécom, is responsible for education, research, innovation, industrial transfer, and scientific culture dissemination. With 2,500 students, 500 staff, and a budget of €50m, it has three campuses dedicated to the industry of the future, health and well-being, and digital sovereignty and microelectronics. It is ranked in the top 15 graduate engineering schools in France and the top 500 universities worldwide.

The 2023-2027 strategy of Mines Saint-Etienne is in line with that of Institut Mines Telecom. It aims to:

  • Support the ecological, digital, and generational transitions and educate the people involved
  • Support national and European sovereignty in microelectronics and digital technology

To support this strategy, it is recruiting a postdoctoral researcher.

Job Description:

The Centre Ingénierie et Santé (CIS) brings together 70 people, including 18 professors in engineering, industrial/computing, biomechanics, and healthcare engineering. Since its creation in 2004, the CIS has been representative of the ability of Mines Saint-Etienne to acquire leadership on innovative themes such as soft tissue biomechanics.

The CIS is part of the SAINBIOSE research unit (Inserm U1059), which brings together researchers from the CIS, the faculty of Medicine from Jean Monnet University, Saint-Etienne University Hospital, Inserm, and the French Blood Establishment. The global scientific objective of SAINBIOSE is a better understanding and of biostress in osteoarticular and cardiovascular pathology.

The research group has 15 years of experience in biomechanics and mechanobiology. We are seeking a postdoctoral researcher to join the Avril's team working on the JuvenTwin project, which aims to establish multiscale digital twins of ageing effects on vascular mechanobiology and to simulate and screen effective rejuvenation treatments.

The work will be carried out at Mines Saint-Etienne, within the SAINBIOSE research unit. The objective of the researcher will be to establish the first vascular applications of our new multiplex imaging platform integrating the latest facility of digital spatial profiling for RNA and proteins. We will extract the spatial variations of the transcriptome (marker genes indicating the patterns of cell phenotypes) of aortic tissues in order to find associations with age effects.

Tasks may change depending on the needs of the department and Mines Saint-Etienne.

Profile Sought:

We are looking for a researcher with a doctoral degree no more than 3 years old, in which case you will be employed as a postdoctoral researcher. If your doctorate is more than 3 years old, you will be employed as a research and development engineer.

You have the following skills, knowledge, and experience:

  • Capacity to successfully integrate a team and a group within a R&D environment
  • Good knowledge of image processing
  • First experience with biomedical applications or molecular biology
  • Expertise in coding (Matlab, Python, Julia)

Why Join Us:

Institut Mines-Telecom is characterised by:

  • A scientific environment of excellence
  • A group with entities throughout France

Mines Saint-Etienne is distinguished by:

  • A privileged working environment with a high student supervision rate and a high environment rate (support and back-up functions)
  • First-rate experimental and digital resources
  • Significant contract research activity (€11m/year in Research and Innovation contracts), mainly with industrial partners
  • 25% international students, Member of the T.I.M.E. network and the EULIST European University
  • A centre for scientific, technical, and industrial culture - La Rotonde - which is unique in France, and which has a major impact on society (> 50,000 visitors per year)
  • Pleasant workplace, easily accessible by public transport and close to motorways
  • Public transport costs reimbursed up to 75% (subject to conditions)
  • Sustainable mobility package
  • Staff committee that subsidises sports, leisure, cultural, and social events and activities
  • The possibility of partial remote working
  • 49 days annual leave

Additional Information:

Recruitment conditions:

  • Fixed-term contract for a period of 12 months (renewable)
  • Desired start date: 1st October 2024
  • Remuneration will be set according to the candidate's profile, based on the rules defined by the Institut Mines Télécom's management framework
  • Full time
  • Position based in Saint-Étienne
  • For internal use:
    • Category II - Job P - Post doctorant according to the Management Framework

The position is open to all, with accommodation available on request for candidates with disabilities. The job is open to civil servants and/or the general public. All applications may be subject to an administrative enquiry.

How to apply:

Applications (CV, covering letter, letter of recommendation if applicable) must be submitted on the RECRUITEE platform no later than 15/08/2024.

Candidates selected for an interview will be informed rapidly. Part of the interview will be held in English.

As part of its Equality, Diversity, and Inclusion policy, École des Mines de Saint Etienne is an employer that is committed to fair treatment of all applicants.

For more information:

For further information about the position, please contact:

Stephane AVRIL – Researcher

+33 (0)4 77 42 01 88

For all administrative information, please contact:

Charlotte MOGIER – Human Resources

+33 (0)4 77 42 01 18

Useful links:

Data protection:



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