Investigation of Thyroid Organoids Response to Ionizing Radiation

Job Title: Analysis of Human Normal Thyroid Organoids Response to Ionizing RadiationJob Summary:We are seeking a highly motivated and experienced researcher to join our team at the Institute for Radiological Protection and Nuclear Safety (IRSN) in France. The successful candidate will be responsible for analyzing the response of human normal thyroid...

MissionScientific ContextThyroid exposure to ionizing radiation during childhood is a recognized risk factor for the development of cancers. However, the risk decreases with the dose, and statistical epidemiological methods are no longer applicable. To address this knowledge gap, we are developing an organoid model derived from human normal thyroid tissue,...

Job DescriptionScientific ContextIonizing radiation exposure to the thyroid gland during childhood has been identified as a risk factor for cancer development. However, the impact of low-dose exposure on public health remains unclear. To address this knowledge gap, we are developing an organoid model of human normal thyroid tissue, which reproduces the 3D...

MissionScientific contextExposure to ionizing radiation (IR) during childhood is a recognized risk factor for the development of cancers. However, the impact of low doses on public health remains unclear. To address this question, we are developing an organoid model of human normal thyroid tissue, which reproduces the 3D organization of thyroid follicles and...

Scientific ContextExposure to ionizing radiation during childhood is a recognized risk factor for thyroid cancer development. However, the impact of low-dose radiation on thyroid health remains unclear. To address this knowledge gap, we are developing an organoid model of human normal thyroid tissue that reproduces the 3D organization of thyroid...

MissionScientific contextExposure to ionizing radiation during childhood is a recognized risk factor for thyroid cancer development. However, the impact of low doses on public health remains unclear. To address this question, we are developing an organoid model of human normal thyroid tissue, which reproduces the 3D organization of thyroid follicles and...

\t\tMission\tScientific Context\tThyroid exposure to ionizing radiation (IR) during childhood, following radioactive iodide contamination or external exposure, is a recognized risk factor for the development of cancers, as epidemiology studies have shown. However, the risk decreases with the dose, and the frequency of spontaneous thyroid cancers increases...

Job DescriptionWe are seeking a highly skilled researcher to join our team at the Institute for Radiological Protection and Nuclear Safety (IRSN). The successful candidate will be responsible for analyzing the response of human normal thyroid organoids to ionizing radiation.Key Responsibilities:Develop and implement protocols for the analysis of thyroid...

MissionEffective intercellular communication is crucial for a tissue to respond to stress, such as irradiation, and restore homeostasis. MicroRNAs (miRNAs) play a key role in this process by regulating gene expression in target cells. The primary objective of this internship is to validate preliminary data identifying potential candidate miRNAs found in cell...

Job DescriptionMissionThe primary objective of this project is to elucidate the mechanisms underlying the cellular responses to radiation-induced DNA damage during myogenic differentiation. This involves investigating the impact of ionizing radiation on the DNA repair processes in myotubes, which are polynuclear cells of skeletal muscle tissue, and comparing...

MissionCell-to-cell communication is crucial for tissue homeostasis, enabling it to respond to stress, such as irradiation. MicroRNAs (miRNAs) play a key role in this process by regulating gene expression in target cells. The main objective of this internship is to validate preliminary data identifying potential candidate miRNAs found in cell culture...

MissionEffective intercellular communication is crucial for tissue homeostasis, enabling it to respond to stressors like irradiation. MicroRNAs (miRNAs) play a key role in this process by regulating gene expression in target cells. The primary objective of this internship is to validate preliminary data identifying potential candidate miRNAs found in cell...

MissionEffective intercellular communication is crucial for tissue homeostasis, enabling it to respond to stressors like irradiation. MicroRNAs (miRNAs) play a vital role in this process by regulating gene expression in target cells. The primary objective of this internship is to validate preliminary data identifying potential candidate miRNAs found in cell...

Project OverviewThe goal of this project is to investigate how myotubes, a type of polynuclear cell found in skeletal muscle tissue, maintain their cellular functions when their nuclei are damaged due to irradiation. This project aims to understand the complex mechanisms of DNA repair and how they impact the genomic integrity of these cells.Research...

Job DescriptionJoin our team at Sopra Steria, a leading European technology company with 56,000 employees in nearly 30 countries. We are recognized for our consulting, digital services, and software publishing activities. Our mission is to help our clients achieve digital transformation and obtain concrete and sustainable benefits. We provide a global...

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MissionWe are seeking a highly skilled researcher to join our team at IRSN to work on a project focused on implementing the coupling between different physical processes involved in gas migration and upscaling results into the continuum scale. This project is part of the EURAD 2 initiative, which aims to develop a comprehensive understanding of the complex...

MissionWe are seeking a highly skilled researcher to join our team at IRSN to work on a project focused on implementing the coupling between different physical processes involved in gas migration and upscaling results into the continuum scale. This project is part of the EURAD 2 initiative, which aims to develop a comprehensive understanding of the complex...

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Technip Energies - A Company Driven by SustainabilityTechnip Energies, a leading engineering and technology company, seeks a highly motivated and detail-oriented individual to join its Ethics & Compliance Department as an Intern.As a member of this dynamic team, you will participate in various activities, including:Business EthicsYou will contribute to the...