Stage M2: The role of miRNA in myogenic cell communication in response to ionizing radiation H/F

MissionThe goal of this project is to understand how myotubes, polynuclear cells of skeletal muscle tissue, in comparison to its mono-nuclear precursors, myoblasts, maintain their cellular functions when one or more of their nuclei are damaged upon irradiation. Interaction of ionizing radiation with living matter induces various types of damage, particularly...

Scientific ContextIonizing radiation exposure to the thyroid gland is a recognized risk factor for cancer development, particularly at high doses. However, the impact of low-dose exposure on thyroid organoids remains unclear. To address this knowledge gap, we are seeking a researcher to investigate the effects of ionizing radiation on human thyroid...

Project OverviewThe goal of this project is to investigate how myotubes, a type of polynuclear cell found in skeletal muscle tissue, maintain their cellular functions when their nuclei are damaged due to irradiation. This project aims to understand the complex mechanisms of DNA repair and how they impact the genomic integrity of these cells.Research...

MissionScientific contextThyroid exposure to ionizing radiation (IR) during childhood, following radioactive iodide contamination or external exposure is a recognized risk factor for the development of cancers by epidemiology studies, but for thyroid doses above 50mGy. As the risk decreases with the dose and the frequency of spontaneous thyroid cancers...

MissionThe goal of this Masters-2 internship project will be to perform experimental validation of a radiation adverse outcome pathway (AOP-). This goal will be achieved via the following specific tasks: a) analysis of transcriptional profiles (RNA-seq) of cells exposed to ionizing radiation; b) identify altered cellular pathways and biological functions...

MissionThe position holder will contribute to the formulation and physicochemical characterisation of emulsions and hydrogels made of hydrophilic or amphiphilic chelating agents at IGPS, and to the assessment of their effectiveness in decontaminating damaged skin or wounds exposed ex vivo to actinides, cesium, or cobalt isotopes using automated Franz...

Technip Energies - Together, pushing the boundaries to shape a sustainable future Technip Energies is a leading engineering and technology company serving the energy transition, with leading positions in Liquefied Natural Gas (LNG), hydrogen and ethylene and with a strong presence in the growing markets of blue and green hydrogen, sustainable chemistry,...

MissionLe stage proposé vise à étudier le rôle des miRNA dans la réponse tissulaire à une exposition localisée aux rayonnements ionisants dans notre modèle préclinique chez la souris. L'étude sera conduite sur les tissus des membres irradiés et controlatéraux prélevés chez des souris exposées à différentes doses de rayonnements conduisant au...

Job DescriptionThe postdoctoral researcher will contribute to the formulation and physicochemical characterization of emulsions and hydrogels made of hydrophilic or amphiphilic chelating agents at IGPS, and to the assessment of their effectiveness in decontaminating damaged skin or wounds exposed ex vivo to actinides, cesium, or cobalt isotopes using...

About Technip EnergiesTechnip Energies is a leading engineering and technology company serving the energy transition, with a strong presence in the growing blue and green hydrogen, sustainable chemistry, and CO2 management markets.With a presence in 34 countries, our 15,000 employees are fully committed to bringing our customers' innovative projects to life,...

MissionExtending the operational life of Pressurized Water Reactors (PWR) is a significant concern for the nuclear industry in general and for French MWe PWR in particular. Indeed, French MWe PWR operation lifetime initially designed for 40 years is planned to be extended to 60 years, and preliminary studies might suggest an extension up to 80 years. The...

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About ForviaWe are a leading global automotive supplier with a rich history spanning over a century.Our company has become the 7th largest global automotive supplier, employing more than 50,000 people in 43 countries.Job DescriptionThis role offers an exciting opportunity to join our dynamic team as an HR Development Specialist in Nanterre, France.As a key...

**Your position and environment**: Our FORVIA Seating Business Group is looking for a Communications Apprentice based in Nanterre, France. Your role is to promote the image of this Business Group, and to ensure that its strategy and performance are well understood internally and externally. The Communications Apprentice reports directly to the Business Group...

Job Description Your position and environment Our FORVIA Seating Business Group is looking for a Communications Apprentice based in Nanterre, France. Your role is to promote the image of this Business Group, and to ensure that its strategy and performance are well understood internally and externally. The Communications Apprentice reports...

**Forvia, a sustainable mobility technology leader**: Join Our Team as a Communications Manager! We are seeking a dynamic Communications Manager to join our Group Content Factory. In this role, you will **propose and implement initiatives to promote FORVIA’s comprehensive technology portfolio and innovation capabilities to both internal and external...

About UsTechnip Energies is a leading engineering and technology company serving the energy transition, with strong positions in Liquefied Natural Gas (LNG), hydrogen and ethylene.We have a presence in 34 countries, with over 15,000 employees fully committed to bringing our customers' innovative projects to life.We offer a dynamic international environment...

New trends and expectations are reshaping the automotive industry. Inspired by the exciting new challenges associated with this revolution, Faurecia anticipates the future of mobility developing cutting-edge solutions for smart life on board and sustainable mobility. If you’re willing to contribute and create value for tomorrow’s cleaner and smarter...

About Technip EnergiesWe are a world-leading engineering and technology player for the energy transition, with leading positions in the sectors of Liquefied Natural Gas (LNG), hydrogen and ethylene. Our expertise is built on 65 years of history and a presence in 34 countries, where we have a team of 15,000 employees committed to accelerating the energy...

Job Description Forvia, a sustainable mobility technology leader  Join Our Team as a Communications Manager! We are seeking a dynamic Communications Manager to join our Group Content Factory. In this role, you will propose and implement initiatives to promote FORVIA’s comprehensive technology portfolio and innovation capabilities to both...