Research Assistant
Il y a 2 mois
**Grade***: G4
**Contractual Arrangement***: Fixed-term appointment
**Contract Duration (Years, Months, Days)**
**Job Posting***: Jan 3, 2023, 3:09:02 AM
**Closing Date***: Jan 25, 2023, 4:59:00 PM
**Primary Location***: France-Lyon
**Organization***: Nutrition and Metabolism
**Schedule***: Full-time
**PURPOSE OF POSITION**
The International Agency for Research on Cancer (IARC), is the cancer agency of the World Health Organization (WHO) and is based in Lyon, France. The objective of the IARC is to promote international collaboration in cancer research.
The goal of the Nutrition and Metabolism Branch (NME) is to provide robust scientific evidence on the role of nutrition, obesity, and metabolic dysfunction in cancer development that can translate to both clinical and population-level interventions and to public health policy. NME aims to go beyond what may be considered the traditional domains of nutrition in cancer research and fully exploit methodological advances in molecular techniques to implement an integrated, multidisciplinary programme of research. Given the potential for advances in molecular profiling to help overcome methodological challenges in nutrition research and delineate the underlying biological pathways, emphasis is placed on conducting molecular epidemiological research that integrates metabolomics, hormone measurements, the microbiome, and genomics, within population-based cohorts and intervention studies.
The aim of the position is to support metabolomics studies, in particular untargeted metabolomics, by performing laboratory analyses and related activities on a liquid chromatography-mass spectrometry (LC-MS) based platforms.
The Research Assistant is expected to:
- Plan, execute, and document sample analyses based on requests of the supervisor, by using methods and protocols with standard operation procedures (SOPs)
- Operate and maintain mass spectrometry instruments (LC-MS), plan manufacturer’s maintenance visits, contribute to the laboratory quality control and assessment of the instruments’ long-term performance
- Plan and execute acquisition of consumables, shipment and storage of samples
- Support the development of laboratory methods and practices, software tools, and databases for metabolomics.
**DESCRIPTION OF DUTIES**
Under the supervision of the Scientist NME, and overall guidance of Scientist (NME Head) the incumbent will perform the below tasks:
- **Sample analysis with the LC-MS instrumentation**
- Upon request of the supervisor, conducts sample analyses on the LC-MS platforms including independent coordination of shipments, storage, preparation, and analysis of biological samples, entailing:
- Communication with collaborators for shipment and reception of samples
- Sample storage at IARC
- Planning analytical batches including sample randomization schemes
- Sample preparation and analysis according to SOPs and delivery of raw data/quantitative results to the supervisor
- Documentation of all activities in an electronic notebook
- **Operation and maintenance of the LC-MS instruments**
- Conducts periodic maintenance and system suitability tests according to SOPs, evaluating the test results, and reporting adverse findings to the supervisor.
- Communicates with the manufacturer for repairs/maintenance when requested by the supervisor and schedules as well as organizes the preventative maintenance visits of the instrument manufacturer.
- **Other related laboratory operations**
- Ensures timely response to analysis requests, by keeping track of a stock of consumables and functioning of the laboratory equipment.
- Evaluates the need for consumable purchases and handles purchase orders.
- **Participate in the development of analytical methods, software tools, and databases**
- Contributes to the development of new laboratory methods and assays as well as provides feedback and assistance for the development of methods and metabolite databases, assessment of data quality, and metabolite identification and quantification based on supervisor’s request.
- Supports the supervisor in writing and updating the SOPs.
**COVID-19 MEASURES**
**WHO COMPETENCIES**
- Teamwork*
- Respecting & promoting individual and cultural differences*
- Communication*
- Producing results.
- knowing and managing yourself.
**SKILLS**
- Experience in working in analytical chemistry laboratory, preferably with human biospecimens
- Experience in operating an LC-MS instrument
- Fluency and efficiency in use of Windows and ability to quickly learn new software
- Ability to adapt to work based on SOPs and documentation of the tasks
- Ability to work in a timely manner in a project-based environment as a member of a team that includes diverse cultural backgrounds
**REQUIRED QUALIFIC**A**TIONS**
**EDUC**A**TION**
**Essential**: At minimum, graduation from secondary school with scientific orientation or equivalent, plus specialized training as a laboratory technician or research assis
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