Stage M2: The role of miRNA in myogenic cell communication in response to ionizing radiation H/F

MissionEffective intercellular communication is crucial for a tissue to respond to stress, such as irradiation, and restore homeostasis. MicroRNAs (miRNAs) play a key role in this process by regulating gene expression in target cells. The primary objective of this internship is to validate preliminary data identifying potential candidate miRNAs found in cell...

MissionEffective intercellular communication is crucial for tissue homeostasis, enabling it to respond to stressors like irradiation. MicroRNAs (miRNAs) play a key role in this process by regulating gene expression in target cells. The primary objective of this internship is to validate preliminary data identifying potential candidate miRNAs found in cell...

MissionEffective intercellular communication is crucial for tissue homeostasis, enabling it to respond to stressors like irradiation. MicroRNAs (miRNAs) play a vital role in this process by regulating gene expression in target cells. The primary objective of this internship is to validate preliminary data identifying potential candidate miRNAs found in cell...

Job DescriptionMissionThe primary objective of this project is to elucidate the mechanisms underlying the cellular responses to radiation-induced DNA damage during myogenic differentiation. This involves investigating the impact of ionizing radiation on the DNA repair processes in myotubes, which are polynuclear cells of skeletal muscle tissue, and comparing...

MissionScientific ContextThyroid exposure to ionizing radiation during childhood is a recognized risk factor for the development of cancers. However, the risk decreases with the dose, and statistical epidemiological methods are no longer applicable. To address this knowledge gap, we are developing an organoid model derived from human normal thyroid tissue,...

Scientific ContextIonizing radiation exposure to the thyroid gland is a recognized risk factor for cancer development, particularly at high doses. However, the impact of low-dose exposure on thyroid organoids remains unclear. To address this knowledge gap, we are seeking a researcher to investigate the effects of ionizing radiation on human thyroid...

Job DescriptionScientific ContextIonizing radiation exposure to the thyroid gland during childhood has been identified as a risk factor for cancer development. However, the impact of low-dose exposure on public health remains unclear. To address this knowledge gap, we are developing an organoid model of human normal thyroid tissue, which reproduces the 3D...

MissionScientific contextExposure to ionizing radiation (IR) during childhood is a recognized risk factor for the development of cancers. However, the impact of low doses on public health remains unclear. To address this question, we are developing an organoid model of human normal thyroid tissue, which reproduces the 3D organization of thyroid follicles and...

Job Title: Analysis of Human Normal Thyroid Organoids Response to Ionizing RadiationJob Summary:We are seeking a highly motivated and experienced researcher to join our team at the Institute for Radiological Protection and Nuclear Safety (IRSN) in France. The successful candidate will be responsible for analyzing the response of human normal thyroid...

Project OverviewThe goal of this project is to investigate how myotubes, a type of polynuclear cell found in skeletal muscle tissue, maintain their cellular functions when their nuclei are damaged due to irradiation. This project aims to understand the complex mechanisms of DNA repair and how they impact the genomic integrity of these cells.Research...

Scientific ContextExposure to ionizing radiation during childhood is a recognized risk factor for thyroid cancer development. However, the impact of low-dose radiation on thyroid health remains unclear. To address this knowledge gap, we are developing an organoid model of human normal thyroid tissue that reproduces the 3D organization of thyroid...

MissionScientific contextExposure to ionizing radiation during childhood is a recognized risk factor for thyroid cancer development. However, the impact of low doses on public health remains unclear. To address this question, we are developing an organoid model of human normal thyroid tissue, which reproduces the 3D organization of thyroid follicles and...

\t\tMission\tScientific Context\tThyroid exposure to ionizing radiation (IR) during childhood, following radioactive iodide contamination or external exposure, is a recognized risk factor for the development of cancers, as epidemiology studies have shown. However, the risk decreases with the dose, and the frequency of spontaneous thyroid cancers increases...

Job DescriptionWe are seeking a highly skilled researcher to join our team at the Institute for Radiological Protection and Nuclear Safety (IRSN). The successful candidate will be responsible for analyzing the response of human normal thyroid organoids to ionizing radiation.Key Responsibilities:Develop and implement protocols for the analysis of thyroid...

Technip Energies: A Leading Engineering and Technology CompanyTechnip Energies is a leading engineering and technology company serving the energy transition, with a strong presence in the growing markets of blue and green hydrogen, sustainable chemistry, floating offshore wind turbines, and CO2 capture and storage.Within the Ethics & Compliance department,...

Technip Energies: A Leader in the Energy Transition At Technip Energies, we are committed to shaping a sustainable future through innovative engineering and technology solutions. Our company is a leading player in the energy transition, with a strong presence in LNG, hydrogen, and ethylene markets. As an apprentice in the Ethics & Compliance...

Job DescriptionThe position holder will contribute to the development and physicochemical characterization of emulsions and hydrogels containing hydrophilic or amphiphilic chelating agents at IGPS, and to the assessment of their effectiveness in decontaminating damaged skin or wounds exposed ex vivo to actinides, cesium, or cobalt isotopes using automated...

Technip Energies: A Leader in the Energy TransitionAt Technip Energies, we are committed to shaping a sustainable future through innovative engineering and technology solutions. Our company serves the energy transition with leading positions in Liquefied Natural Gas (LNG), hydrogen, and ethylene, as well as a strong presence in blue and green hydrogen,...

Job DescriptionWe are seeking a highly motivated and experienced postdoctoral researcher to join our team at IRSN. The successful candidate will contribute to the development of novel topical formulations for the decontamination of injured skin exposed to radionuclides.Key ResponsibilitiesDesign and formulate novel topical formulations for skin...

Job DescriptionJoin our team as an Analyste Crédit en stage H/F and contribute to the success of Crédit Agricole CIB.About the RoleWe are seeking a motivated and detail-oriented individual to join our team as an Analyste Crédit en stage H/F. As an Analyste Crédit en stage H/F, you will be responsible for analyzing and evaluating credit risk, as well as...